Analysis of Anion Gap in Premature Suffered from Hyperbilirubinemia

VernacularTitle:高胆红素血症早产儿血清阴离子隙分析的意义
Author: Qiwu WU ; Ping ZHAO
Publication Type:Journal Article
Keywords: Anion gap; Infant,premature; Hyperbilirubinemia,Neonatorum
From: Chinese Journal of Primary Medicine and Pharmacy 2012;(22):3379-3380
CountryChina
Language:Chinese
Abstract: Objective To investigate the changes of the anion gap(AG)in the premature suffered from hyperbilirubinemia,to provide the basis for treatment.Methods The serum electrolyte,the renal function and the liver function in 94 premature babies suffered from hyperbilirubinemia were tested,and then calculated the value of AG,while the arterial blood gas analyses were done in 36 cases.Results 44 cases had high AG(46.81％),44 cases had normal AG(46.81％)and 6 cases had low AG(6.38％).The increase of AG was directly proportional to the concentration of Na+in blood,while was inversely proportion to the concentration of HCO3-.There was no close relationship between the AG and BUN,Scr in the serum.Conclusion The incidence rate of metabolic acidosis poisoning was high in premature suffered from hyperbilirubinemia with high AG,so the routine test of blood electrolyte,renal function and arterial blood gas should be done.Calculate the value of AG to guide the treatment,and to avoid correcting the acid by the alkali blindly.