Characteristics and evaluation of acute liver failure in children
10.3760/cma.j.issn.1673-4912.2012.06.002
- VernacularTitle:小儿急性肝功能衰竭的特征与评估
- Author:
Quan WANG
;
Suyun QIAN
- Publication Type:Journal Article
- Keywords:
Acute liver failure;
Clinical characteristics;
Children
- From:
Chinese Pediatric Emergency Medicine
2012;(6):560-563
- CountryChina
- Language:Chinese
-
Abstract:
Acute liver failure (ALF) is rare in children but carries high mortality.It can progress to multi-organ failure and death.The etiology,clinical manifestations,diagnosis and prognosis of pediatric acute liver failure (PALF) are different from that of adults,and vary with age.The classic adult symptoms are often absent in children and the clinical encephalopathy may not be present.Children correctly diagnosed with well-characterized causes of PALF may benefit from the early implementation of directed medical therapies.Early recognition,diagnosis,and identification of prognostic factors will help in optimizing treatment and selecting patients for liver transplantation or artificial support,and improved their survival chances.
