Resistin and atherosclerotic stroke
10.3760/cma.j.issn.1673-4165.2012.12.011
- VernacularTitle:抵抗素与动脉粥样硬化性卒中
- Author:
Tianbao ZHU
;
Huaiyu LI
- Publication Type:Journal Article
- Keywords:
Resistin;
Stoke;
Brain Ischemia;
Cerebral Infarction;
Atherosclerosis;
Risk Factors;
Biological Markers
- From:
International Journal of Cerebrovascular Diseases
2012;(12):948-951
- CountryChina
- Language:Chinese
-
Abstract:
Resistin is a recently discovered polypeptide hormone.Studies have shown that resistin is closely associated with atherosclerosis by promoting inflammatory response and adhesion of vascular endothelial cells,transformation from macrophages to foam cells,vascular smooth muscle cell proliferation and migration,increasing plaque instability,as well as promoting carbohydrate and lipid metabolism disorders,etc.Resistin can promote the occurrence and development of ischemic cerebrovascular disease.It may become a potential biological marker and intervention target.