Transcranial magnetic stimulation combined with body-weight-supported treadmill treating after incomplete spinal cord injury
10.3760/cma.j.issn.0254-1424.2012.011.004
- VernacularTitle:重复经颅磁刺激联合减重步行训练治疗慢性不完全性脊髓损伤患者的临床疗效观察
- Author:
Yanping XIANC
;
Feng TANG
;
Feng XIAO
;
Fengqin WEI
;
Yan ZHANG
;
Xiaolin HUANG
- Publication Type:Journal Article
- Keywords:
Spinal cord injury;
Repetitive transcranial magnetic stimulation;
Body-weight-supported treadmill training;
H reflex;
Functional magnetic resonance imaging
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2012;(11):814-817
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effects of repetitive transcranial magnetic stimulation (rTMS) combined with body-weight-supported treadmill training (BWSTT) on patients with incomplete spinal cord injury (SCI).Methods Four patients with chronic incomplete SCI participated in this study.They were first treated with rTMS and then BWSTT training.They were assessed with clinical measures of function.Two of the four patients were assessed in terms of their H reflex,and using functional magnetic resonance imaging (fMRI) and a balance performance monitor (BPM).Results In two of the four patients,American spinal injury association (ASIA) clinical measures of motor and sensory function improved,as did 10 m walking speed and their sense of effort.In static balance tests,the sway path and sway area of the two patients both decreased.These improvements lasted for 3 weeks after the intervention.The two patients' maximum H reflex amplitude and the H/M amplitude ratio decreased.The fMRI results showed progressive enlargement of the activation volume of the movement-related M1 region after treatment.Conclusion High-frequency rTMS combined with BWSTT may improve motor function,elevate excitability of spinal motor neurons and improve the plasticity of the cerebral cortex in chronic incomplete SCI patients.
