Management and outcomes of patients with ST-elevation myocardial infarction in Liaoning province
10.3760/cma.j.issn.1671-7368.2012.12.008
- VernacularTitle:辽宁地区ST段抬高心肌梗死诊治现状调查
- Author:
Bo ZHANG
;
Daming JIANG
;
Xuchen ZHOU
;
Jun LIU
;
Hao ZHU
;
Yujiao SUN
;
Lina REN
;
Yuan GAO
;
Yuze LI
;
Guoxian QI
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Myocardial reperfusion;
Therapy;
Cross-sectional studies
- From:
Chinese Journal of General Practitioners
2012;(12):902-906
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the management and outcomes of patients with ST-segment elevation myocardial infarction (STEMI) in Liaoning province.Methods The data were collected from a prospective and multicenter registry study including 8 tertiary hospitals and 12 secondary hospitals in Liaoning province.Total 1429 patients with acute STEMI admitted to hospitals from June 2009 to June 2010 were included in the study.A unified follow-up questionnaire was applied on patient discharged.Results The average age of patients was (63 ± 13)years.37.4% of patients recognized the disease as heart disease and 39.7% were transported by emergency ambulance with a median symptom-to-door time of 150 min.52.9% patients underwent emergency reperfusion therapy,including fibrinolytic therapy (24.4%) and primary percutaneous coronary intervention (PCI,28.1%).The in-hospital treatment included aspirin (99.6%),clopidogrel (81.9%),statins (90.1%),low molecular weight heparin (89.5%),β-blocker (66.0%),angiotensin converting enzyme inhibitor (ACEI)/ angiotensin receptor blocker (ARB)(66.6%).The in-hospital mortality was 10.7% ; the mortality in females was higher than that in males (18.3% vs.7.9%,P < 0.01) and the mortality in older patients (≥ 65 years) was higher than that in younger patients (<65 years)(17.0% vs.5.2%,P <0.01).The follow-up treatment included:aspirin (81.1%),clopidogrel (45.0%),statins (61.0%),β-blocker (48.3%),ACEI/ARB (42.4%).The follow-up mortality was 5.0% after hospital discharge.Conclusions Longer pre-hospital delay is commonly seen in STEMI patients.There is still certain gap of emergency reperfusion therapy and the evidence-based medication with related clinical guidelines of STEMI management in Liaoning.