Protective role of ERp46 in palmitic acid-induced endoplasmic reticulum stress
10.3760/cma.j.issn.1000-6699.2012.12.015
- VernacularTitle:ERp46在棕榈酸诱导的内质网应激中的保护作用
- Author:
Danling CHEN
;
Jingnan XIANG
;
Liyong YANG
- Publication Type:Journal Article
- Keywords:
ERp46;
Palmitic acid;
Endoplasmic reticulum stress;
Lipoapoptosis
- From:
Chinese Journal of Endocrinology and Metabolism
2012;(12):1012-1015
- CountryChina
- Language:Chinese
-
Abstract:
Detection of the possible role of ERp46,new endoplasmic reticulum protein,on palmitic acid-inducedendoplasmic reticulum stress-apoptosis pathway in βTC6 cells for the new treatment of type 2 diabetes.Results showed that ERp46 played a protective role in palnutic acid-induced cell apoptosis by decreasing the endoplasmic reticulum stress response through three pathway.
