Progress of microRNAs involved in type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2012.11.025
- VernacularTitle:微小RNA在2型糖尿病相关机制中的研究进展
- Author:
Dongxue ZHANG
;
Lulu CHEN
;
Yunfei LIAO
- Publication Type:Journal Article
- Keywords:
microRNA;
Diabetes mellitus,type 2;
Insulin resistance;
Islet dysfunction;
Diabetes related complications
- From:
Chinese Journal of Endocrinology and Metabolism
2012;(11):944-947
- CountryChina
- Language:Chinese
-
Abstract:
Type 2 diabetes mellitus (T2DM) is one of the most serious public health problems,while the detailed mechanisms underlying its pathology remain obscure.MicroRNAs (miRNAs),which are single-stranded noncoding RNAs,are considered to be involved in various pathological processes,especially in T2DM.MiRNA has become a noval player in insulin resistance,islet dysfunction,and even in the diabetes related complications.