Effect of topical anesthesia with compound lidocaine cream coated on the tracheal tube on extubation response in patients undergoing Han-uvulopharyngoplasty
10.3760/cma.j.issn.0254-1416.2012.11.011
- VernacularTitle:复方利多卡因乳膏涂抹气管导管行表面麻醉对改良悬雍垂腭咽成形术患者拔管反应的影响
- Author:
Defeng SUN
;
Lin YANG
;
Yue WU
;
Zhan YU
;
Yi WEI
;
Lijie WANG
- Publication Type:Journal Article
- Keywords:
Lidocaine;
UNGUENTUM;
Intubation,endotracheal;
Stress
- From:
Chinese Journal of Anesthesiology
2012;(11):1328-1330
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of topical anesthesia with compound lidocaine cream coated on the tracheal tube on extubation response in patients undergoing Han-uvulopharyngoplasty (H-UPPP).Methods Eighty-four patients,aged 28-48 yr,weighing 91-108 kg,scheduled for elective H-UPPP,requiring tracheal intubation under general anesthesia,were equally and randomly divided into 2 groups:compound lidocaine cream group (group L) and control group (group C).The compound lidocaine cream 2-3 g were coated on the tracheal tube cuff and exterior before induction of anesthesia in group L,while the paraffin oil was coated in group C.Mean arterial pressure (MAP),HR and pulse oxygen saturation were recorded before induction of anesthesia,at the end of infusion of anesthetics,during extubation and 5 min after extubation (T1-4).Blood samples were taken from the forearm veins on the noninfusion side at T1-4 for detection of plasma adrenergic and norepinephrine concentrations.Cardiovascular events during extubation were recorded.Results Compared with group C,MAP and HR were significantly decreased at T3,4,the incidences of hypotension and tachycardia were decreased,the plasma adrenergic and norepinephrine concentrations were significantly decreased at T2-4 in group L (P ＜ 0.05).Conclusion Topical anesthesia with compound lidocaine cream coated on the tracheal tube can effectively reduce the extubation response in the patients undergoing H-UPPP.
