The efficacy of α1 receptor-blocker in the treatment of voiding symptoms after transurethral electrovaporization

VernacularTitle:选择性α1受体阻滞剂在经尿道前列腺汽化电切术后早期的应用价值
Author: Feng LI
Publication Type:Journal Article
Keywords: Prostatic hyperplasia; Transurethral resection of prostate; Adrenergic alphaantagonists; Drugtherapy
From: Chinese Journal of Geriatrics 2013;(2):178-179
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical efficacy of a1 receptor blocker (ARB) in treating voiding symptoms after TUVP and investigate its mechanism.Methods A total of 80 patients with BPH were randomly divided into 2 groups (40 cases for each).The patients in treatment group were given α1 receptor blocker at 1 day after TUVP for 30 days,while patients in control group did not receive ARB treatment.The indices such as Qmax,BRU,IPSS and QOL before operation versus 30 days after operation were monitored and analyzed.The therapeutic effect was compared between 2 groups.Results The changes of Qmax,IPSS,QOL and BRU after α1 receptor blocker treatment had significant difference between the two groups [(20.35 ± 1.62)ml/s,(11.25± 5.02)ml,(4.91 ± 1.30)scores,(1.13±0.30) scores vs.(3.92±1.20)ml/s,(529.24±7.19)ml,(31.33±2.56) scores,(5.48±0.42) scores,all P＜ 0.05].All the data of treatment group showed significant improvement compared with those of control group.Conclusions The α1 receptor blocker was effective in treating voiding symptoms after TUVP.