Clinical effects of finasteride on preventing prostate hyperplasia with acute urinary retention

VernacularTitle:非那雄胺预防前列腺增生急性尿潴留的临床观察
Author: Yuan LIU
Publication Type:Journal Article
Keywords: Prostatic hyperplasia; Urinary retention
From: Chinese Journal of Geriatrics 2012;(12):1085-1086
CountryChina
Language:Chinese
Abstract: Objective To study the effect of finasteride on preventing prostate hyperplasia with acute urinary retention.Methods Totally 626 patients with benign prostatic hyperplasia (BPH) were randomly divided into treatment group (316 cases) and control group (310 cases),followed up for 3 years.The incidence of acute urinary retention and prostate volume changes were analyzed.Results There were 3 cases of acute urinary retention in treatment group (1.0 ％),9 cases in control group (2.9％) (x2 ＝5.37,P＜0.05).In treatment group,the average prostate volume was reduced about 23.6％ compared with before taking the medicine,on the contrary,prostate volume was averagely increased 12.3％ in control group.Conclusions Finasteride can reduce the risk of acute urinary retention by narrowing the prostate volume in patients of benign prostatic hyperplasia.