CD40-CD40 ligand in pediatric disease
10.3760/cma.j.issn.1673-4408.2013.01.024
- VernacularTitle:CD40-CD40配体与儿科疾病
- Author:
Ranran LI
- Publication Type:Journal Article
- Keywords:
CD40-CD40 ligand;
Pediatric disease
- From:
International Journal of Pediatrics
2013;(1):80-83
- CountryChina
- Language:Chinese
-
Abstract:
CD40-CD40 ligand (CD40-CD40L) cross-linking,an important cell signaling transduction pathway in immune response,is involved in the regulation of cellular and humoral immune.CD40-CD40L signaling pathway abnormalities can lead to immune system disorders and incur immune pathological reaction.A variety of common pediatric diseases,such as immunodeficiency diseases,inflammatory diseases and autoimmune diseases,are associated with CD40-CD40L signaling transduction pathway abnormalities.The relationship between CD40-CD40L and the above-mentioned diseases is of clinical significance.
