Serum level of prostate specific antigen and its relationship with prostatic biopsy in health check-up populations
10.3760/cma.j.issn.1674-0815.2012.06.013
- VernacularTitle:体检人群前列腺特异性抗原检测水平及其同前列腺穿刺相关性的研究
- Author:
Xin CHEN
;
Ming LIU
;
Jianye WANG
;
Ling ZHU
;
Gang WAN
;
Lanjun MA
;
Yanyan ZHAO
- Publication Type:Journal Article
- Keywords:
Physical examination;
Antigens;
Prostate
- From:
Chinese Journal of Health Management
2012;(6):402-404
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study serum level of prostate specific antigen (PSA) by age and its relationship with positive prostatic biopsy.Methods A total of 8818 adults who underwent PSA scanning at Health Chek-up Center of Beijing Hospital during July 2009 and July 2010 were retrospectively studied,40 of whom performed prostatic biopsy.Linear regression was used to assess the relation of PSA with age,while Chi-square test was used to compare positive prostatic biopsy in different PSA groups.Results Serum PSA of more than 4 μg/L was more commonly seen in the elderly group (40 ～ year-old group 1.4％,50 ～ yearold group 1.9％,60 ～ year-old group 9.2％,70 ～ year-old group 15.5％,80 year-old group 17％ ; P ＜0.001 ; RR =0.196).In those whose PSA was ＞ 20 μg/L,6 (83.3 ％) were found to have positive prostatic biopsy; and the figure was 10 (50.0％) or 24 (24.0％) when PSA was ＜4 μg/L or 4-10 μg/L group (P =0.048).Conclusions Age was positively correlated with PSA,although no linear correlation was confirmed.Higher serum PSA level (＞ 4 μg/L) may be more common in elderly people and those with a positive prostatic biopsy.
