Microglia and white matter injury in preterm infants
10.3760/cma.j.issn.1673-4408.2012.06.023
- VernacularTitle:小胶质与早产儿脑白质损伤的研究进展
- Author:
Fang SONG
- Publication Type:Journal Article
- Keywords:
Premature infants;
White matter damage;
Microglial cells
- From:
International Journal of Pediatrics
2012;(6):618-620
- CountryChina
- Language:Chinese
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Abstract:
Periventricular leukomalacia in premature infants is the most common brain injury.It often results in spastic cerebral palsy,cognitive and behavioral abnormalities and other sequelae.The microglia is the primary immune response cell in brain,and it plays an important role in balancing mechanism for the defense response and brain injury.The suppression of its activated reaction can reduce the cytotoxic effect and pathological damage in the early phase.
