Liver transplantation in 64 liver donors with hepatic steatosis
10.3760/cma.j.issn.1007-8118.2013.02.007
- VernacularTitle:64例脂肪变性供肝临床肝移植疗效分析
- Author:
Qifa YE
;
Yingzi MING
;
Jie ZHAO
;
Guizhu PENG
;
Yi ZHANG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Steatosis liver donor
- From:
Chinese Journal of Hepatobiliary Surgery
2013;(2):105-107
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To investigate the results of liver transplantation using steatosis liver donors in order to provide a scientific basis for the use of marginal donors.Methods From 2002 to 2011,80 of 407 were steatosis liver donors.There were 69 males and 11 females.Their age ranged from 20-54 years old.Sixteen donor livers with severe fatty liver and reperfusion injury were not used.The remaining 64 livers were divided into a S1 group (mild steatosis,n=22),a S2 group (moderate steatosis,n=25),and a S3 group (severe steatosis,n=17).A S0 group was used as a control (randomly selected fat-free liver,n=80).Results The occurrence rates of delayed graft function (DGF) in the S0,S1,S2,S3 groups were 5％,9.1％,20％,29.41％,respectively.Primary nonfunctioning occurred in 2 cases of the S3 group,which represented a 11.76％ of the S3 group (2/17),and 3.12％ of the total 64 cases (2/64).Conclusions Although the incidence rate of DGF was higher in the steatosis liver donor groups than the S0 group,there was no correlation in the mortality rate of the S1-S3 group within one year of transplantation.Attentions should be paid to the treatment of complications after steatosis liver transplantation.By minimizing ischemia-reperfusion injury,improving microcirculation,strengthening routine therapy and reducing the amount of immunosuppression,the same results could be achieved using steatosis donor liver and normal liver for transplantation.
