The role of MHCⅡ + T lymphocytes in immune tolerance induction
10.3760/cma.j.issn.1007-8118.2012.11.023
- VernacularTitle:T细胞表达MHCⅡ类分子在器官移植免疫耐受中的意义
- Author:
Haiyang WANG
;
Jiqiao ZHU
;
Xianliang LI
;
Dazhi CHEN
- Publication Type:Journal Article
- Keywords:
MHCⅡ antigen;
T-lymphocytes;
Organ transplantation;
Immune tolerance
- From:
Chinese Journal of Hepatobiliary Surgery
2012;(11):880-883
- CountryChina
- Language:Chinese
-
Abstract:
Traditionally,antigen presenting cells were shown to express MHC Ⅱ antigens.However,some researchers have demonstrated that a subset of T lymphocytes could express MHCⅡ antigens in some situation.Its regulatory mechanism and biological effects remains challenging to researchers.This review provides an overview of the results of these MHC Ⅱ + T lymphocytes regarding to the generation,mechanisms,and the role in immune tolerance induction,aim to provide some insights in clinical immune tolerance induction.
