Analysis of chromosomal aberration in seven medical staffs suspected with exposure to ionizing radiation

VernacularTitle:七例疑似受照的医疗工作人员染色体畸变分析
Author: Lin HAN ; Fengling ZHAO ; Xiai WANG ; Ping WANG ; Feng JIANG ; Yumin Lü
Publication Type:Journal Article
Keywords: Ionizing radiation; Medical staff; Chromosomal aberration
From: Chinese Journal of Radiological Medicine and Protection 2012;(6):607-609
CountryChina
Language:Chinese
Abstract: Objective To investigate the chromosomal aberrations in seven medical staffs suspected with exposure to ionizing radiation and to speculate its possible causation.Methods The hospital staffs,including 6 females and 1 male,worked in a clinical laboratory where a CT room was located downstairs.The thickness of precast slab between these two rooms was 6 cm.Peripheral blood lymphocytes of seven staffs were examined for conventional chromosomal aberrations.Results The frequencies of dicentrics in the peripheral lymphocytes of 4 females were from 0.40％ to 1.60％ that was significantly higher than the spontaneous frequency of dicentrics (0.03％,x2 =36.79,P ＜ 0.05).The translocation was observed in the lymphocytes from all subjects with frequencies from 0.33％ to 1.20％,obviously higher than its spontaneous frequency of 0.01％ (x2 =42.90,P ＜ 0.05).Conclusion These staffs suffer from ionizing radiation.