Risk factors for in-hospital mortality in patients underwent pertaneous transhepatic biliary drainage with malignant obstructive jaundice: a prospective study
10.3760/cma.j.issn.1005-1201.2012.12.014
- VernacularTitle:恶性梗阻性黄疸经皮肝穿刺胆道引流术后院内死亡危险因素探讨
- Author:
Hongtao NIU
;
Zejing WANG
;
Renyou ZHAI
;
Jianfeng WANG
;
Qiang HUANG
;
Dingke DAI
- Publication Type:Journal Article
- Keywords:
Jaundice,obstructive;
Drainage;
Hospital mortality;
Risk factors
- From:
Chinese Journal of Radiology
2012;(12):1114-1118
- CountryChina
- Language:Chinese
-
Abstract:
Objective In-hospital mortality rate in patients undergoing percutanous transhepatic biliary drainage for malignant obstructive jaundice remained high.This study aimed to assess pre-,intra-and post-procedure risk factors which were independently associated with increased in-hospital mortality.Methods One hundred and fifty-five consecutive patients with malignant obstructive jaundice received initial PTBD drainage.Twenty-five pre-procedure,4 intra-procedure and 6 post-procedure factors potentially related with in-hospital mortality were assessed by univariate and multivariate analysis.Results In-hospital mortality rate was 16.8％ (26/155).Of 25 pre-procedure variables analysed,Child-Pugh classification C,creatinine (≥ 6.93 μmol/L) and quality of life (≤ 30) were found to be significant in univariate and multivariate analysis.Increased mortality was seen in this study with two or more risk factors,significantly different from patients who had none or one risk factor(P ＜0.01).None of the intra-procedure factors were important in identifying patients at risk of death.Multivariate analysis indicated post-PTBD cholangitis and unsuccessful drainage as post-procedure risk factors that correlated with in-hospital death.Conclusions Three pre-procedure and two post-procedure risk factors were identified associated with in-hospital mortality.
