The relationship of antepartum different gestational age of foramen ovale size and postpartum ostium secundum atrial septal defect
10.3760/cma.j.issn.1004-4477.2012.12.007
- VernacularTitle:产前不同孕周胎儿卵圆孔大小与产后继发孔房间隔缺损的相关性研究
- Author:
Lin LIU
;
Yihua HE
;
Zhian LI
;
Lianzhong ZHANG
;
Jianjun YUAN
- Publication Type:Journal Article
- Keywords:
Ultrasonography,prenatal;
Heart septal defect,atrial;
Foramen ovale
- From:
Chinese Journal of Ultrasonography
2012;(12):1031-1034
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship of the antepartum foramen ovale (FO),the ratios of foramen ovale and aorta (FO/AO) and postpartum ostium secundum atrial septal defect (ASD).Methods Nine hundred fifty-eight fetuses were divided into 5 groups by gestational age,18-22 weeks,23-26 weeks,27-30 weeks,31-34 weeks,35-40 weeks.The diameter of FO and aortic (AO) and FO/AO were measured by fetal echocardiography,the postpartum echocardiography were followed up more than 12 months after birth.ANOVA was used to compare FO,AO,FO/AO with different gestational age.Regression equation estimate was used to compare the relationship of FO and AO with gestational age.Independent sample T test was used to compare FO and FO/AO with postpartum ostium secundum ASD and postpartum normal heart.Results There was significant difference in FO and AO among 5 groups(P =0.000),FO and AO increased with increasing gestational age.There was significant difference in antepartum FO,FO/AO between postpartum ostium secundum ASD and postpartum normal heart (P =0.000).Conclusions Antepartum FO and FO/AO provide clinical value in observing postpartum ostium secundum ASD.
