The role of spatio-temporal image correlation with tomographic ultrasound imaging in the prenatal diagnosis of conotruncal defects
10.3760/cma.j.issn.1004-4477.2012.12.005
- VernacularTitle:时间-空间关联成像联合超声断层显像模式在产前诊断圆锥动脉干畸形中的应用
- Author:
Jin XU
;
Yihua HE
;
Zhian LI
;
Shicheng QIN
;
Heli LI
;
Lijuan ZHAO
;
Xiuli ZHANG
;
Suyun HOU
- Publication Type:Journal Article
- Keywords:
Ultrasonography,prenatal;
Heart defects,congenital;
Conotruncal defects
- From:
Chinese Journal of Ultrasonography
2012;(12):1026-1030
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application value of spatio-temporal image correlation (STIC) combined with tomographic ultrasound imaging(TUI) in the prenatal diagnosis of conotruncal defects(CTD).Methods Two-dimensional(2D) fetal echocardiography to screen and TUI-STIC volumes from 1508 cases of fetuses of high risk with congenital heart disease.Postnatal work-up and pathological results were available for all fetuses with CTD.Results Thirty nine cases with CTD were found by TUI-STIC while thirty five cases were found by 2D echocardiography,but TUI-STIC had new findings and corrected the diagnosis in 9 cases as compared with 2D echocardiography.The sensitivity,specificity,positivity predictive value,negative predictive value and accuracy of TUI-STIC in evaluating CTD were 97.5 ％,100％,100 ％,99.9 ％ and 99 ％.The Kappa value of consistency test between 2DE and TUI-SIC was 0.244(P ＜ 0.01),McNemar test showed that the difference was statistically significant (P ＜ 0.01).Conclusions TUI-STIC allows a complete sequential analysis of fetal conotruncal defects and supplying additional information over 2D fetal echocardiography,it could improve the prenatal diagnosis rate.TUI-STIC is helpful in diagnosis of prenatal conotruncal defects.
