A research of left ventricular global and segmental longitudinal systolic function and synchronization in patients with hypertrophic cardiomyopathy by tissue motion annular displacement
10.3760/cma.j.issn.1004-4477.2012.12.002
- VernacularTitle:肥厚型心肌病左心室整体与节段纵向收缩功能及同步性的组织运动瓣环位移研究
- Author:
Lei ZUO
;
Liwen LIU
;
Shengjun TA
;
Yandan SUN
;
Xiaodong ZHOU
;
Liping YANG
;
Wei QI
;
Bin MA
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Cardiomyopathy,hypertrophic;
Ventricular function,left
- From:
Chinese Journal of Ultrasonography
2012;(12):1017-1021
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value and feasibility of tissue mitral annular displacement (TMAD) in the assessment of left ventricular global and segmental longitudinal systolic function and synchronization in patients with hypertrophic cardiomyopathy.Methods The study population consisted of 39 on-obstructive hypertrophic cardiomyopathy (nHCM) patients and 39 healthy volunteers matched by gender and age.Left ventricular global and segmental longitudinal were measured by speckle tracking imaging(STI).The mitral annular displacement (MAD) (anterioseptal,posterioseptal,anterior,lateral,posterior and inferior sites,respectively),peak of time (PT) and left ventricular systolic dyssynchrony index (SDI) were measured by TMAD.The correlation between LSR and MAD was analyzed,and the parameters of MAD and SDI for tow groups were compared.Results The rate of effectively track segments of TMAD was significantly higher than that of STI(98.7％ vs 77.9％,P ＜0.001).There were high correlationship between segmental LSR and MAD(r =-0.784,P ＜0.001),and global and MADglobal (r =-0.897,P ＜0.001).Compared with the control group,MAD of six spots and MADglobal were significantly decreased (P ＜ 0.001,respectively),SDI was significantly increased(P ＜0.001).Conclusions TMAD is a sensitive and reproducible method for the assessment of LV longitudinal functionin patients with nHCM.
