Influence of Shenmai injection on immune function in the treatment of locally advanced non-small cell lung cancer patients with concurrent chemoradiotherapy
10.3760/cma.j.issn.1008-6706.2012.23.006
- VernacularTitle:参麦注射液对局部晚期非小细胞肺癌同步放化疗患者免疫功能的影响
- Author:
Yiliang MENG
;
Xiaohua LI
;
Guangyou HUANG
;
Chengle HUANG
;
Shengwu HUANG
;
Jianxian CHEN
;
Xuesong ZHENG
;
Ganque DENG
- Publication Type:Journal Article
- Keywords:
Cancer,non-small cell lung;
Immune;
Shenmai injection
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;(23):3531-3532
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Shenmai injection combined concurrent chemoradiotherapy on immune function in patients with locally advanced non-small cell lung cancer.Methods A total of 80 patients with locally advanced non-small cell lung cancer were randomly divided into treatment group and control group.In treatment group,40 patients received simultaneous three-dimensional conformal radiotherapy combined with TP(docetaxel+cisplatin)chemotherapy,while given Shenmai injection in the process of concurrent chemoradiotherapy.In control group,40 patients only received chemoradiotherapy.The changes of T cell subsets were observed between the two groups.Results It showed no significant differences in percentages of CD+3,CD+4,CD+16CD+56and CD+4/CD+8 ratio between two groups pre-treatment(all P＞0.05).There were no significant adverse reactions occurred after received Shenmai injection in treatment group.Conclusion It play an important role in improving immune function of patients with locally advanced non-small cell lung cancer who received Shenmai injection combined concurrent chemoradiotherapy.
