Intraductal papillary mucinous neoplasm of the pancreas: clinical characteristics and treatment outcomes of 361 patients
10.3760/cma.j.issn.1674-1935.2012.06.003
- VernacularTitle:胰管内乳头状黏液性肿瘤361例的临床特征
- Author:
Lei WANG
;
Tian XIA
;
Zhuan LIAO
;
Duowu ZOU
;
Zhendong JIN
;
Yiqi DU
;
Xianbao ZHAN
;
Xiangui HU
;
Gang JIN
;
Chenghao SHAO
;
Jianming ZHENG
;
Li WANG
;
Zhaoshen LI
- Publication Type:Journal Article
- Keywords:
Pancreas;
Intraductal papillary mucinous neoplasm;
Diagnosis;
Therapy
- From:
Chinese Journal of Pancreatology
2012;(6):371-374
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the clinical characterization of intraductal papillary mucinous neoplasm of pancreas (IPMNs) and to improve the understanding of IPMNs.Methods Three hundred and sixty-one patients with IPMN at Shanghai Changhai Hospital between 1993 and 2012 were retrospectively analyzed.Results Among 361 cases of IPMNs,241 were men and 120 were female,with a female to male ratio of 2.6∶1.Mean age of the patients was 62 years old (16 ～ 87 years old).The duct type included the main duct in 102 patients (28.3％),a branch duct in 109 (30.2％),and mixed ducts in 150 (41.6％).The most common symptom at presentation is pancreatitis,which occur in 167 patients (46.3％).The sensitivity for the detection of IPMN was 80.2％ by ERCP,76.9％ by MRCP,63.9％ by CT,and 50.5％ by EUS.One hundred and twenty-nine patients (35.7％) were operated and diagnosed with 87 (67.2％) IPMA,21 (16.4％) IPMB,10(8.2％) IPMC(CIS) and 10 (8.2％) had invasive carcinomas.The 5-year survival rates of IPMA,IPMB,IPMC,and invasive carcinomas were 100％,100％,66.5％,and 44.7％,respectively.Conclusions IPMNs were fregrently occured is 60 years old,half of patients had acute pancreatitis history and the frequtly attack,mixed type is most anatomy type,and the outcome after surgery is good.
