Hypoxia inducible factor-1α and tumor
10.3760/cma.j.issn.1673-422X.2012.012.003
- VernacularTitle:缺氧诱导因子1α与肿瘤
- Author:
Rui WANG
;
Shengtao LIAO
;
Yunlai LIU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Hypoxia-inducible factor 1;
Diagnosis;
Therapy
- From:
Journal of International Oncology
2012;(12):889-892
- CountryChina
- Language:Chinese
-
Abstract:
Hypoxia inducible factor-1α(HIF-1α) is usually highly expressed in tumor cells,and can promote tumor growth.HIF-1α is correlated with tumor condition,the diagnosis and the prognosis.Therefore,HIF-1α can be used for tumor treatment in the level of transcriprion,pro-transcriprion and target.It is possible to improve the treatment efficiency,and to lengthen patients lifespan.
