GRIM-19 gene and tumor
10.3760/cma.j.issn.1673-422X.2012.012.002
- VernacularTitle:GRIM-19基因与肿瘤
- Author:
Yupei SHAO
;
Xiaoyun WAN
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Genes,tumor suppressor;
STAT3 transcription factor
- From:
Journal of International Oncology
2012;(12):886-888
- CountryChina
- Language:Chinese
-
Abstract:
Genes associated with retinoid-interferon mortality (GRIM) are a group of genes,and GRIM-19 is one of the core genes.Studies have found that GRIM-19 is down-regulated in many types of tumors,and may be a new type of tumor suppressor and a new target for chemotherapy in tumors.