Ezrin protein in tumor metastasis associated signaling pathways
10.3760/cma.j.issn.1673-422X.2012.011.005
- VernacularTitle:埃兹蛋白与肿瘤转移相关信号通路的研究进展
- Author:
Meili XI
;
Xin LU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Neoplasm metastasis;
Signal transduction;
Ezrin protein
- From:
Journal of International Oncology
2012;(11):815-817
- CountryChina
- Language:Chinese
-
Abstract:
Ezrin protein plays an important role in morphogenesis,motility,adhesion.Moreover,Ezrin protein participates in multiple steps of the process of tumor invasion and metastasis.In the progress of tumor metastasis,Ezrin protein is related to several signaling pathways such as Rho mediated signaling pathways,hepatocyte growth factor (HGF) pathways,Fas mediated cell apoptosis signaling pathways,phosphatidyl inositol 3-kinase (PI3K)-Akt pathways,and in which it plays different regulatory role.
