Esophageal cancer related gene 4 in tumor
10.3760/cma.j.issn.1673-422X.2012.011.002
- VernacularTitle:人食管癌相关基因4与肿瘤
- Author:
Chaoqun HONG
;
Yanjie YOU
;
Jihong HUANG
- Publication Type:Journal Article
- Keywords:
Genes,tumor suppressor;
Neoplasms;
Tumor markers,biological;
Diagnosis
- From:
Journal of International Oncology
2012;(11):806-808
- CountryChina
- Language:Chinese
-
Abstract:
Esophageal cancer related gene 4 (ECRG4) serves as a tumor suppressor gene through interacting with NF-κB and p53 pathways.Multiple studies have demonstrated that the down-regulated expression of ECRG4 occurs in a variety of cancer types,indicating a potential application of ECRG4 as a molecular diagnostic marker as well as a therapeutic target