Advances in pathogenic mechanisms of enterovirus 71
10.3760/cma.j.issn.1673-4408.2013.01.020
- VernacularTitle:肠道病毒71型致病机制研究进展
- Author:
Xue LIU
- Publication Type:Journal Article
- Keywords:
Enterovirus 71;
Cell tropism;
Cell apoptosis;
Immune responses
- From:
International Journal of Pediatrics
2013;(1):68-70
- CountryChina
- Language:Chinese
-
Abstract:
Enterovirus 71 (EV71) is one of the major pathogens that cause hand foot and mouth disease.Epidemics and pandemics have been periodically reported worldwide.EV71 also can cause serous complications and lead death in children.The mechanisms of EV71 cause serious complications has remained unclear,may relate to many factors,including cell tropism,cell death and host immune responses.This article reviews the recent advances in the identification of factors determining EV71 cell tropism,the associated mechanisms of viral infection-induced cell death and the interplay between EV71 and immunity.
