De novo neoplasms after liver transplantation: a clinical study
10.3760/cma.j.issn.1007-8118.2013.02.006
- VernacularTitle:肝移植术后新发恶性肿瘤的临床研究
- Author:
Xinyu LI
;
Jiye ZHU
;
Guangming LI
;
Lei HUANG
;
Xisheng LENG
- Publication Type:Journal Article
- Keywords:
De novo neoplasm;
Liver transplantation;
Post-operative
- From:
Chinese Journal of Hepatobiliary Surgery
2013;(2):102-104
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To determine the incidence of de novo neoplasms after liver transplantation and methods of prevention.Methods The clinical data of 605 patients after liver transplantation carried out from May 2000 to December 2010 in our centre were analysed.The patient's gender,age,primary disease and the clinical characteristics of post-transplantation de novo neoplasms were analysed.Results The incidence of de novo post-transplantation neoplasms was 1.80％.There was one case of post-transplantation lymphoproliferative disorders (PTLD),one case of pulmonary blastoma,one case of acute myelogenous leukemia,one case of bladder tumor,one case of gastric carcinoma,one case of sigmoid colon carcinoma,one case of carcinoma of rectum,one case of renal clear cell carcinoma and two cases of hepatocellular carcinoma.Conclusion There was a low incidence of de novo posttransplantation neoplasm in our centre than that reported in the West,probably because of variations in patient selection,immunosuppression regimens used,patients' age and different patient ethnic groups.Early diagnosis and treatment of de novo neplasm helped to improve prognosis.
