Strategy of anti-angiogenesis and antiangiogenic drugs in NSCLC
10.3760/cma.j.issn.1673-422X.2012.012.012
- VernacularTitle:非小细胞肺癌抗血管生成治疗药物和策略
- Author:
Xiangfei ZHAO
;
Qing NIE
;
Jingbo KANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Angiogenesis inhibitors;
Molecular targeted therapy
- From:
Journal of International Oncology
2012;(12):916-920
- CountryChina
- Language:Chinese
-
Abstract:
Development and metastasis of NSCLC are closely related to angiogenesis.Several distinct groups of vascular-targeted therapies have evolved:anti-VEGF monoclonal antibody,small molecules inhibitors,vascular disrupting agents,endothelial cell growth inhibitors,et al.Antiangiogenic treatment could make longer survival than conventional treatment.The strategy of anti-angiogenic drugs combined conventional treatment is being studied.