EML4-ALK fusion gene in non-small cell lung cancer
10.3760/cma.j.issn.1673-422X.2012.011.015
- VernacularTitle:EML4-ALK与非小细胞肺癌相关研究进展
- Author:
Meng WANG
;
Jiyuan YANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell;
Lung neoplasms;
Tumor markers
- From:
Journal of International Oncology
2012;(11):848-850
- CountryChina
- Language:Chinese
-
Abstract:
EML4-ALK fusion oncogene represents a new molecular target which appears mainly in lung adenocarcinoma.EML4-ALK is detected more frequently in young non-small-cell lung cancer patients who never or light smoke.ALK inhibitors(crizotinib)for the treatment of the EML4-ALK-positive non-small cell lung cancer has a high response rate.This finding can improve the individual treatment of non-small cell lung cancer.
