Wnt signaling pathway and tumor
10.3760/cma.j.issn.1673-422X.2012.011.009
- VernacularTitle:Wnt信号通路与肿瘤的研究进展
- Author:
Juan GU
;
Xuedong WANG
;
Zhaolin PAN
;
Lihua HUANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Neoplastic stem cells;
Wnt signaling pathway
- From:
Journal of International Oncology
2012;(11):827-830
- CountryChina
- Language:Chinese
-
Abstract:
Wnt signaling pathway is not only closely related to tumor invasion and metastasis,such as cancer cells migration and adhesion,extracellular matrix degradation,and angiogenesis,but also plays an important role in self-renewal,proliferation and differentiation of tumor stem cells.Progress has been made in high specific genes drug development and targeted therapy against the Wnt signaling pathway.
