Cullin1 and malignant tumors
10.3760/cma.j.issn.1673-422X.2012.011.006
- VernacularTitle:Cullin1蛋白与恶性肿瘤
- Author:
Weimin WANG
;
Jianliang DENG
;
Yan ZHOU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Cullin1
- From:
Journal of International Oncology
2012;(11):818-820
- CountryChina
- Language:Chinese
-
Abstract:
Cullinl is a member of the cullin genome.The cullin1 assembly complex has typical ubiquitin ligase activity,and mediates cell cycle proteins,especially cancer-associated protein degradation process,an then effectively regulates the cell cycle progression.Cullin1 play an important role in the genesis and development of malignant tumors.
