Comparison of thrombomodulin in acute cerebral infarction patients with different blood glucose levels
10.3760/cma.j.issn.1673-4904.2012.33.004
- VernacularTitle:不同血糖水平急性脑梗死患者血栓调节蛋白比较
- Author:
Xiaomeng FENG
;
Meng JI
;
Yuan XU
- Publication Type:Journal Article
- Keywords:
Brain infarction;
Diabetes mellitus;
Thrombomodulin
- From:
Chinese Journal of Postgraduates of Medicine
2012;(33):9-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the levels of thrombomodulin in acute cerebral infarction patients with different blood glucose levels.Methods Four hundred and eighty-nine patients with acute cerebral infarction were selected including 237 patients of non-diabetes (non-diabetes group),117 patients of diabetes and HbA1c ≤7.0％(diabetes controlled well group) and 135 patients of diabetes and HbA1c ＞7.0％ (diabetes controlled badly group).The level of thrombomodulin was assayed by enzyme-linked immunosorbent assay and compared among three groups.Results The level of thrombomodulin was (2.66 ± 1.20) μg/L in non-diabetes group,(2.80 ± 1.43) μg/L in diabetes controlled well group,(3.22 ±1.60) μ g/L in diabetes controlled badly group.There was the increasing of thrombomodulin among non-diabetes group,diabetes controlled well group and diabetes controlled badly group (P =0.030).There was difference between non-diabetes group and diabetes controlled badly group (P =0.008).Conclusion There is the increasing of thrombomodulin in patients with acute cerebral infarction when their blood glucose rising.
