Effect of percutaneous coronary intervention on level of brain natriuretic peptide of acute myocardial infarction patients

VernacularTitle:经皮冠状动脉介入术对急性心肌梗死患者血浆脑利钠肽水平的影响
Author: Qian WANG
Publication Type:Journal Article
Keywords: Myocardial infarction; Angioplasty,transluminal,percutaneous coronary; Natriuretic peptide,brain
From: Chinese Journal of Primary Medicine and Pharmacy 2012;(24):3701-3702
CountryChina
Language:Chinese
Abstract: Objective To study the level of brain natriuretic peptide of acute myocardial infarction(AMI)patients given percutaneous coronary intervention(PCI).Methods 200 patients with AMI were collected and randomly divided into observation group given PCI and control group given thrombolytic therapy.Then level of BNP 6h,12h,24h and 48h after treatment was detected and cardiac function indexes were observed.Results BNP level of observation group began to reduce from 6h(t=5.382,9.493,12.482,all P＜0.05),control group began to reduce from 12h(t=7.831,12.184,all P＜0.05);ST segment elevation of BNP＜100ng/L group was significantly lower than that of ≥ 100ng/L group(t=9.472,P＜0.05);LVEDD,LVEF were significantly higher than those of ≥ 100ng/L group(t=6.932,5.532,all P＜0.05).Conclusion PCI can decrease level of BNP and improve heart function in a relatively short time and has positive therapeutic significance.