The diagnostic value of 18F-FDG uptake PET/CT score of Lesions for early esophageal lesions
10.3760/cma.j.issn.1008-1372.2012.11.012
- VernacularTitle:病灶18F-FDG摄取PET/CT记分对早期良恶性食管病变的诊断价值
- Author:
Xiaoqian SUN
- Publication Type:Journal Article
- Keywords:
Fluorodeoxyglucose F18/diagnostic use;
Esophageal neoplasms/radiography;
Esophageal neoplasms/radionuclide imaging;
Tomography,X-ray computed;
Tomography,emission-computed
- From:
Journal of Chinese Physician
2012;(11):1483-1485
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study of the diagnostic value of 18 F-FDG(Fluorine-18-fluorodeoxyglucose) uptake PET/CT score of lesions for early esophageal lesions.Methods The study included 36 patients with early malignant esophageal lesions,and the 66 cases with 18 F-FDG uptake increased as benign esophageal lesions.The evaluation score standard for lesion were (1) FDG uptake strength:0 =low,1 =moderate,and 2 =high; (2) FDP intake performance:0 =concentric circles,and 1 =eccentric circular;(3) FDG uptake ability:dispersion =0,and arc =1,focal type =2 ; (3) CT examination showed esophageal normal =0,thickening =1,and mass =2; (5) Site was located in the proximal esophageal 1/3 =0,the intermediate 1/3 =1,and distal 1/3 =2.Results The FDG uptake strength score was 2 points or more for 15 patients (41.8％) and FDG uptake eccentricity ratio score was 1 points or more for 20 patients (55.6％) in early malignant lesion group,and for 12 patients (18.2％) and 7 (10.6％) in benign lesion group,respectively; there was significantly difference between the two groups (x2 =16.22,24.18,P ＜0.01).CT examination esophageal thickness score was 2 points or more for 8 patients (12.1％) in early malignant lesion group and 8 patients (22.2％) in benign lesion group; there was no significantly difference between the two groups (P ＞ 0.05).Early malignant lesion group's largest SUV was higher than benign lesion group (3.3 ±0.9 vs.5.3 ±4.1,t =11.04,P ＜0.01).Focal-partial eccentricity'score threshold was 2 or more,and was different between benign or malignant lesions had sensitivity of 83.3％ and a specificity of 68.3％.Conclusions FDG uptake ability and eccentricity have a certain value in discrimination of malignancy from benign esophageal lesions.
