Congenital heart diseases caused by chromosome abnormality
10.3760/cma.j.issn.1673-4408.2013.01.016
- VernacularTitle:染色体异常致先天性心脏病的研究进展
- Author:
Juan LI
- Publication Type:Journal Article
- Keywords:
Chromosome abnormality;
Congenital heart disease;
Clinical syndrome
- From:
International Journal of Pediatrics
2013;(1):55-58
- CountryChina
- Language:Chinese
-
Abstract:
Chromosome abnormality has recently been recognized as an important cause of congenital heart diseases(CHD).The tiny fragment deformity of the chromosome may lead to many abnormal genes expression.Recent studies have disclosed that CHD is a part of syndrome attributed to chromosome abnormality.This article reviews chromosome abnormality caused by trisomy chromosome,chromosome deletions,Tuner syndrome and Kleinfelte's syndrome as well as incidence,type,mechanism and prognosis of its complicated CHD.
