The differences of adverse drug reaction between children and adults caused by Tanreqing injection

VernacularTitle:儿童和成人使用痰热清注射液后发生不良反应差异分析
Author: Juan XU ; Hongyan WU ; Linqing YAO ; Xin ZHANG
Publication Type:Journal Article
Keywords: Tanreqing injection; Adverse drug reaction (ADR); Children; Adult
From: International Journal of Traditional Chinese Medicine 2013;(2):106-108
CountryChina
Language:Chinese
Abstract: Objective To analyze the differences of adverse drug reactions between children and adults caused by Tanreqing injection,and provide reasonable application of Tanreqing injection.Methods Retrospective research method were adopted to screen out the adverse drug reaction reports caused by Tanreqing injection from drug ADR reports of Drug ADR Monitoring Center affiliated to the Second People's Hospital of Gansu Province from January 2010 to October 2012.Figures of children and adults who used Tanreqing injection were analyzed separately.Results A total of 603 children used Tanreqing injection,among which 5 children appeared ADR (0.83％).A total of 4395 adult used of Tanreqing injection,among which 4 appeared in ADR (0.09％).There was statistical difference between the two groups (x2 =16.07,P＜ 0.05) The incidence rate of ADR in males was more than females either in the adults or in children.Hypersensitivity was the most common ADR.Conclusion ADR of Tanreqing injection in Children was significantly higher than adults.Tanreqing injection should be used carefully and rationally.