The importance of quality assurance in laboratory test for personalized medicine
10.3760/cma.j.issn.1009-9158.2012.11.002
- VernacularTitle:涉及基因扩增的个体化医学检测质量保证的重要性
- Author:
Rui ZHANG
;
Jinming LI
- Publication Type:Journal Article
- Keywords:
Personalized medicine;
Polymerase chain reaction;
Quality control
- From:
Chinese Journal of Laboratory Medicine
2012;(11):963-966
- CountryChina
- Language:Chinese
-
Abstract:
Modern medicine has entered the era of personalized medicine,the most mature of which is based on analysis of the specific gene polymorphism and tumor-related gene mutation and expression detection.Usually the test is related to the PCR technique such as real-time PCR,PCR-sequence,PCR-hybridization (on chip,membrane,latex particles),which leads to the gene amplification process.Now,some laboratories do or will to conduct such clinical tests.But most of them are non-classic clinical laboratories,which belong to the pathology,pharmacy or oncology department.There is a problem in front of us face that is how to standardize the clinical test on the key point of the test including design of the laboratory,collection and handling of the samples,quality control of testing procedure in the laboratory and report and results explanation for personalized testing and establish quality assurance system.
