The efficacy of endoscopic papillectomy for tumors of major duodenal papilla
10.3760/cma.j.issn.1007-5232.2012.12.005
- VernacularTitle:十二指肠乳头肿瘤内镜下切除术34例疗效分析
- Author:
Bin YAN
;
Fengchun CAI
;
Enqiang LINGHU
;
Wen LI
;
Xiuli ZHANG
;
Yunsheng YANG
- Publication Type:Journal Article
- Keywords:
Treatment outcome;
Tumors of major duodenal papilla;
Endoscopic papillectomy;
Complications
- From:
Chinese Journal of Digestive Endoscopy
2012;(12):676-678
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate and analyse the efficacy and safety of endoscopic papillectomy for tumors of major duodenal papilla.Methods The clinical data of thirty-four patients with tumors of major duodenal papilla who were treated by endoscopic papillectomy were retrospectively reviewed,and the clinical outcome was summarized.Results The success rate of endoscopic papillectomy was 94.12% (32/34),and the complete resection was 66.67% (20/30).Short-term complications occurred in 10 cases,including postoperative gastrointestinal bleeding in 7cases and postoperative pancreatitis in 3 cases.Five cases need further surgical intervention for the reason that tumor was too deep in 2 cases,bile duct was invaded in 2 cases and conservational medication was unsuccessful in 1 case.Thirty-three cases were pathologically diagnosed as low grade intraepithelial neoplasia (LGIN),17 cases high grade intraepithelial neoplasia (HGIN),1 case carcinoid and 3 cases adenocarcinoma.The recurrence rate was 23.33 (7/33).tumor recurrence rate of HGIN was higher than that of LGIN(42.86% VS10%,P =0.078).Conclusion Endoscopic papillectomy is an effective method for treating tumors of major duodenal papilla,however,hemorrhage is the main postoperative complication,the recurrence rate is higher in HGIN group.