The efficacy of endoscopic papillectomy for tumors of major duodenal papilla
10.3760/cma.j.issn.1007-5232.2012.12.005
- VernacularTitle:十二指肠乳头肿瘤内镜下切除术34例疗效分析
- Author:
Bin YAN
;
Fengchun CAI
;
Enqiang LINGHU
;
Wen LI
;
Xiuli ZHANG
;
Yunsheng YANG
- Publication Type:Journal Article
- Keywords:
Treatment outcome;
Tumors of major duodenal papilla;
Endoscopic papillectomy;
Complications
- From:
Chinese Journal of Digestive Endoscopy
2012;(12):676-678
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate and analyse the efficacy and safety of endoscopic papillectomy for tumors of major duodenal papilla.Methods The clinical data of thirty-four patients with tumors of major duodenal papilla who were treated by endoscopic papillectomy were retrospectively reviewed,and the clinical outcome was summarized.Results The success rate of endoscopic papillectomy was 94.12％ (32/34),and the complete resection was 66.67％ (20/30).Short-term complications occurred in 10 cases,including postoperative gastrointestinal bleeding in 7cases and postoperative pancreatitis in 3 cases.Five cases need further surgical intervention for the reason that tumor was too deep in 2 cases,bile duct was invaded in 2 cases and conservational medication was unsuccessful in 1 case.Thirty-three cases were pathologically diagnosed as low grade intraepithelial neoplasia (LGIN),17 cases high grade intraepithelial neoplasia (HGIN),1 case carcinoid and 3 cases adenocarcinoma.The recurrence rate was 23.33 (7/33).tumor recurrence rate of HGIN was higher than that of LGIN(42.86％ VS10％,P =0.078).Conclusion Endoscopic papillectomy is an effective method for treating tumors of major duodenal papilla,however,hemorrhage is the main postoperative complication,the recurrence rate is higher in HGIN group.
