Analysis of associated factors in secondary hyperparathyroidism of continuous ambulatory peritoneal dialysis patients
10.3760/cma.j.issn.1001-7097.2012.12.006
- VernacularTitle:持续性非卧床腹膜透析患者继发性甲状旁腺功能亢进相关因素分析
- Author:
Hongmei ZHOU
;
Qingdong XU
;
Zhihua ZHENG
;
Xiao YANG
;
Xueqing YU
- Publication Type:Journal Article
- Keywords:
Peritoneal dialysis;
Hyperparathyroidism,secondary;
Epidemiology;
Regression analysis
- From:
Chinese Journal of Nephrology
2012;(12):933-936
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prevalence and associated factors of secondary hyperparathyroidism (SHPT) in continuous ambulatory peritoneal dialysis (CAPD) patients.Methods A cross-section study was performed.A total of 639 eligible participants undergoing CAPD treatment more than three months in our peritoneal dialysis center from July 2011 to January 2012 were recruited in the study.All the patients were divided into SHPT group and non-SHPT group according to the intact parathyroid hormone (iPTH) level,and the associated factors of SHPT were investigated through Logistic regression analysis.Results The prevalence of SHPT was 46.95% (300/639).Logistic regression analysis demonstrated that lower hemoglobin,hypocalcemia,hyperphosphatemia,higher alkaline phosphatase,higher Scr,higher nPCR and low calcium dialysate were independent influencing factors of SHPT.Conclusions The prevalence of SHPT is quite high in CAPD patients.Abnormal calcium-phosphorus metabolism,renal anemia,high protein diet and low calium dialysate may affect the SHPT.