Clinicopathological characteristics of inflammatory myofibroblastic tumor: analysis of 173 cases

VernacularTitle:炎性肌纤维母细胞瘤173例临床病理特征分析
Author: Qin XIANG ; Yingan JIANG ; Hui SUN ; Guifang YANG ; Jun LIN
Publication Type:Journal Article
Keywords: Inflammatory myofibroblastic tumor; Diagnosis; Treatment
From: Chinese Journal of General Practitioners 2012;(10):769-771
CountryChina
Language:Chinese
Abstract: The clinicopathological data of 173 cases of inflammatory myofibroblastic tumor (IMT)were retrospectively analyzed.Among them 125 were males and 48 females with a mean age of 47.9 y (5-78 y).The lesions of 117 cases were located in lungs,41 cases in eyes,8 in ileocecum,2 in liver,2 in spleen,1 in abdominal wall,1 in maxillary sinus and 1 in face.The average diameter of lesions were 3.5 cm,ranging from 1.0 cm to 7.0 cm.The clinical manifestations were not specific,depending on the locations of tumor.The imaging examinations were helpful for diagnosis.The prcsence of slender-spindled myofibroblasts and proliferation of fibroblast cells,with infiltration of chronic inflammatory cells were the basic histopathological features of the disease.Combined with the histological characteristics and immunohistochemical staining IMT can be differentiated from other spindle cell tumors.Appropriate surgical resection is the main treatment for IMT.