Safety and efficacy of endoscopic multiband mucosectomy for early esophageal carcinoma and intraepithelial neoplasia
10.3760/cma.j.issn.1007-5232.2012.08.007
- VernacularTitle:早期食管癌和上皮内瘤变多环黏膜套切术的疗效和安全性评价
- Author:
Fangyu WANG
;
Jiong LIU
;
Baisi YUAN
;
Xinhua ZHANG
;
Jiandong WANG
;
Youke LU
;
Xiaoqin XU
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Intraepithelial neoplasia;
Endoscopic multiband mucosectomy;
Therapy
- From:
Chinese Journal of Digestive Endoscopy
2012;29(8):441-445
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effectiveness of endoscopic multiband mucosectomy ( EMBM ) for early cancer and precancerous lesions of the esophagus. Methods From August 2007 to December 2011,EMBM was performed on 46 patients (25 males and 21 females) with the average age of 59.0 (35-82) yr.All lesions were margined under NBI,with 2 to 13 cm in diameter (median 4 cm),and occupying at most two-third of the circumference of the esophagus.Of 46 patients,41 (89.1％ ) accepted deep sedation by intravenous injection of propofol.All patients were followed up with endoscopy at 1,6,12 months after the operation.Results A total of 48 lesions were resected completely by EMBM with 1-11 processes.During the procedure,controllable bleeding occurred in 3 cases and micro-perforation occurred in 1,which was cured by metal clip.Histopathological diagnoses revealed 3 cases of intramucosal squamous carcinoma,19 high grade intraepithelial neoplasia,17 low grade intraepithelial neoplasia,and 7 inflammatory hyperplasia.No recurrence was found during the follow-up of 1 to 53 months.Conclusion EMBM is effective and safe for the treatment of early cancer and precancerous lesions of the esophagus.Appropriate indication and manipulation can decrease complication occurrence.
