Research advances on CO2 pneumoperitoneum promoting invasion and metastasis of gastrointestinal cancer

VernacularTitle:CO2气腹促进胃肠道肿瘤侵袭转移的研究进展
Author: Liuhua WANG ; Jie CHEN
Publication Type:Journal Article
Keywords: Neoplasm metastasis; CO2 pneumoperitoneum; Surgicd procedures,minimally invasive
From: Cancer Research and Clinic 2012;24(7):498-500
CountryChina
Language:Chinese
Abstract: The laparoscopic surgery is increasingly widely used in the treatment of malignant gastrointestinal cancer.Its technical feasibility has been recognized,however,there are disagreements in the evaluation of its safety,the tumor metastasis of port-site and intra-abdominal after operation has been the focus of controversy in medical community.Its major impact mechanism including the change of peritoneal microenvironment,immunity,mechanical pressure of pneumoperitoneum,biological behavior of tumor cells and so on.The specification must be taken before surgery,strictly control the laparoscopic gastrointestinal cancer surgery indications,minimize the pneumoperitoneum pressure,shortem operative time,with He gas instead of CO2 pneumoperitoneum or free pneumoperitoneum laparoscopic techniques and other effective measures to reduce the risk of tumor metastasis.