Clinical study of the treatment of elderly advanced malignant tumor by radioactive 125I seed implantation

VernacularTitle:放射性125I粒子治疗老年人晚期恶性肿瘤的临床研究
Author: Yueyun XIE ; Xueyuan LIU ; Zhongping BAO ; Qing REN
Publication Type:Journal Article
Keywords: Radioactive 125I seed; Aged; Malignant neoplasms; Radiotherapy
From: Cancer Research and Clinic 2012;24(6):414-416
CountryChina
Language:Chinese
Abstract: Objective To investigate the efficacy of CT guided radioactive 125I seed implantation on elderly patients with advanced malignancies.Methods 78 cases of elderly patients with malignant were collected and divided into two groups.41 cases of the treatment group were treated with CT guided radioactive 125I seed implantation.Particle activity was 29.6 MBq.The prescription dose was 90-110 Gy.37 cases of the control group were treated with optimized supportive care.Data from all of patients were to review and followup observation in short term efficacy,quality of life and side efforts.Results The total effective rate was 92.7 ％(38/41)and the disease control rate was 97.6 ％(40/41)in the treatment group.The control group was in the effective rate and 16.2 ％(16/37)in the disease control rate.The quality of life of the treatment group was higher than those in the control group(P＜0.05).And there is no obviously side efforts.Conclusion The treatment of elderly patients with advanced malignant tumors by 125I seed implantation was a safe and effective method.It can improve the quality of patients' life.