Research progress of decoy receptor 3 in cancer
10.3760/cma.j.issn.1006-9801.2012.05.027
- VernacularTitle:诱骗受体3与肿瘤的研究进展
- Author:
Qingfeng YUE
;
Yonghe WANG
- Publication Type:Journal Article
- Keywords:
Tumor necrosis factor decoy receptors;
Neoplasms;
Apoptosis;
Research
- From:
Cancer Research and Clinic
2012;24(5):354-357
- CountryChina
- Language:Chinese
-
Abstract:
Decoy receptor 3(DcR3) gene expresses highly in some malignant tumors,it involves cellular proliferation regulation, inhibition of apoptosis, immune escape and tumor angiogenesis by competitively blocking the Fas/FasL, LIGHT and TL1 A/DR3 signal pathway, therefore it deeply relates to the malignant tumors's generation and progression.DcR3 is supposed to be the new tumor-specific marker that may cast the light to the tumor generation,development,prevention,diagnosis,treatment,prognosis and effect observation.DcR3 is expected to be open a new chapter in clinical application.
