Advanced research of Fascin protein expression in human tumor
10.3760/cma.j.issn.1006-9801.2012.05.028
- VernacularTitle:Fascin蛋白与肿瘤的研究进展
- Author:
Guijie LIU
- Publication Type:Journal Article
- Keywords:
Fascin;
Actin;
Cell movement;
Neoplasms
- From:
Cancer Research and Clinic
2012;24(5):358-360
- CountryChina
- Language:Chinese
-
Abstract:
Fascin is an actin-bundling protein that is normally expressed in mesenchymal tissue and the nervous system. Many recent studies have shown that fascin was highly expressed in many human tumors and played a significant role in tumor proliferation, invasion, and metastasis. Fascin expression is also an independent factor correlated with poor patient prognosis and decreased survival rate. Fascin can be explored as a new molecular target for cancer treatment,thus can improve tumor patients' prognosis.
