A Case of Neonatal Lupus with Abnormal Liver Function Test and Skin Lesion.
- Author:
Ju Young CHUNG
1
;
Myoung Jae CHEY
Author Information
1. Department of Pediatrics, Sanggyepaik Hospital, Inje University College of Medicine, Seoul, Korea. pedchung@sanggyepaik.ac.kr
- Publication Type:Case Report
- Keywords:
Lupus;
Neonate
- MeSH:
Antibodies;
Child;
Heart Block;
Heart Diseases;
Humans;
Infant, Newborn;
Liver Function Tests*;
Liver*;
Placenta;
Skin*
- From:Korean Journal of Pediatrics
2005;48(1):85-87
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neonatal lupus(NL) is characterized by typical clinical features and the presence of maternal auto- antibodies. The principal serologic markers of NL are anti-Ro/SSA or anti-La/SSB maternal auto- antibodies, which are transferred across the placenta and can be detected for the first few months of the affected child. The major clinical manifestations are cardiac disease, notably congenital heart block, and cutaneous lupus lesions. Hepatobiliary disease is relatively rare clinical manifestation of NL. We experienced a case of NL with abnormal liver function test and skin lesion.