Analysis of intracranial electroencephalogram records during seizure onset using wavelet transform

VernacularTitle:小波分析用于颅内电极记录发作起始脑电图信号的研究
Author: Jia CHEN ; Fengjun LIU ; Wenjing ZHOU ; Xun WU
Publication Type:Journal Article
Keywords: Epilepsy; Electroencephalography; Electrodes,implanted
From: Chinese Journal of Neurology 2012;45(4):229-232
CountryChina
Language:Chinese
Abstract: Objective To study the wavelet entropy of intracranial electrode recording electroencephalogram (EEG) during the seizure onset,and explore the prospect of applying it for automatic detection of EEG.Methods Twenty-eight seizure events of 9 epilepsy patients whose outcome were Engel class Ⅰ were retrospective analyzed,by comparing the pre-ictal,initial ictal and ictal wavelet energy entropy variations of both seizure onset zone (SOZ) contacts and non-SOZ contacts.Results The wavelet energy entropy of SOZ contacts increased from pre-ictal (0.053 ± 0.047 ) to initial ictal (0.326 ± 0.250),while it declined during the ictal (0.138 ± 0.097,F =30.904,P =0.000).There was no obvious change of the wavelet energy entropy of non-SOZ contacts in different periods.By further applying time-window wavelet entropy to the detection of intracranial EEG,the results showed that the time-window wavelet energy entropy could be sensitive to reflect the seizure onset time and electrodes.Conclusion The wavelet energy entropy of contacts inside SOZ increased significantly at scizurc onset,and this conclusion can be used to assist in presurgical localization of epilepsy.