Research progress on leptomeningeal metastases of solid carcinoma
10.3760cma.j.issn.1006-9801.2012.03.023
- VernacularTitle:恶性实体肿瘤脑膜转移的研究进展
- Author:
Zhenyu PAN
;
Ailin WANG
- Publication Type:Journal Article
- Keywords:
Meninges;
Diagnosis;
Neoplasm metastasis
- From:
Cancer Research and Clinic
2012;24(3):208-210
- CountryChina
- Language:Chinese
-
Abstract:
Leptomeningeal metastasis (LM),with a high omission rate in diagnosis in approximately 5 ％～8 ％ of all patients, is increasingly recognized as a lethality complication. The diagnosis of LM remains challenges,but commonly can be established by CSF cytology or by definitive neuroimaging. Although a combination of focal radiotherapy,intrathecal chemotherapy,and systemic chemotherapy may be necessary to achieve optimal treatment of patients, but prognosis is unacceptable and therapy remains palliative in most patients.
