The Value of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for the Diagnosis of Intrapulmonary Lesions
10.3760/cma.j.issn.1001-4497.2012.04.014
- VernacularTitle:支气管内超声引导针吸活检术在肺内病变诊断中的应用
- Author:
Hui ZHAO
;
Zuli ZHOU
;
Desong YANG
;
Kezhong CHEN
;
Xiao LI
;
Fengwei LI
;
Yun LI
;
Guanchao JIANG
;
Jun WANG
- Publication Type:Journal Article
- Keywords:
Endobronchial ultrasound;
Transbronchial needle aspiration;
Lung cancer;
Diagnosis
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2012;28(4):230-232
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the diagnosis of intrapulmonary tumors located adjacent to the central airway.MethodsThe study was retrospective,from September 2009 to September 2011,33 patients with pulmonary masses located close to the central airways suspected to be lung cancer were accessed by EBUS-TBNA.Conventional bronchoscopic biopsy before EBUSTBNA was nondiagnostic in all cases.If EBUS-TBNA did not result in a formal pathological diagnosis of malignancy,patients were subsequently referred for a surgical procedure.ResultsOf the 33 patients,EBUS-TBNA confirmed lung cancer in 29 cases (4 small cell lung cancer,25 non-small cell lung cancer).Four patients were not confirmed by EBUS-TBNA,3 cases were diagnosed as squamous cell carcinoma by thoracoscoopy or thoracotomy,the other one was a pulmonary inflammatory lesion diagnosed by thoracoscopy.The sensitivity,specificity,accuracy,negative predictive value and positive predictive value of EBUS-TBNA for the diagnosis of intrapulmonary lesions was 90.2％,100％,90.9％,25％,and 100％,respectively.The procedure was uneventful,and there were no complications.ConclusionEBUS-TBNA is an effective tool with a high yield for the diagnosis of intrapulmonary lesions located adjacent to the central airway.
